Primary CNS lymphoma in a patient on Adalimumab (Humira) therapy for chronic plaque psoriasis.

Adalimumab (Humira) is a recombinant human monoclonal antibody against tumor necrosis factor alpha (TNF- α), which works by blocking the interaction of TNF- α with its cell-surface receptors, thereby limiting the progression of inflammatory pathways.

Its use is approved for several autoimmune conditions including chronic plaque psoriasis for which it has been prescribed as a first-line biologic treatment. Increased risks of malignancy, particularly non-melanoma skin cancer and non-CNS lymphomas have been reported with use of this drug, however, there have been no reports of CNS lymphomas.

Here, we report the case of a 43-year old male who presented for evaluation following recent speech difficulty and a generalized tonic-clonic seizure. He has a medical history significant for plaque psoriasis on treatment with adalimumab for 4 months.

An MRI brain with contrast showed a well defined rounded enhancing lesion in the left temporal lobe with circumferential vasogenic edema. There was mass effect noted. A CT chest, abdomen and pelvis was unremarkable. He underwent excisional biopsy and the preliminary intraoperative pathology report revealed a diagnosis of high-grade lymphoma.

Individual Reaction Mix 2

G065-2 200 reactions
EUR 167.00

Anti-EIF4A1/2/3 Antibody

A03922-2 100ug/vial
EUR 334.00

Anti-Fascin 2/FSCN2 Antibody

A07840-2 100ug/vial
EUR 294.00

Anti-ErbB 2/ERBB2 Antibody

A00010-2 100ug/vial
EUR 334.00

Anti-Bcl-2/BCL2 Antibody

A00040-2 100ug/vial
EUR 334.00

Anti-Angiopoietin-2/ANGPT2 Antibody

A00370-2 100ug/vial
EUR 334.00

Dr. P Kit-Solution 2

K2021010-2 6 ml
EUR 120.00
Description: Can be used for various proteomics studies in both normal and pathological cases. It is an excellent control and suitable for educational purposes. This product is prepared from whole tissue homogenates and has undergone SDS-PAGE quality control analysis. The protein is stored in a buffer with protease inhibitor cocktail fo prevent degradation.

pLenti-CARM1 shRNA-2 Plasmid

PVTBAV03691-2 2 ug
EUR 356.00

pLenti-CTLA4 shRNA-2 Plasmid

PVTBAV05689-2 2 ug
EUR 356.00

pLenti-FOXM1 shRNA-2 Plasmid

PVTBAV08732-2 2 ug
EUR 356.00

pLenti-JUN shRNA-2 Plasmid

PVTBAV11741-2 2 ug
EUR 356.00

pLenti-LHX6 shRNA-2 Plasmid

PVTBAV12881-2 2 ug
EUR 356.00

pLenti-MAGEA3 shRNA-2 Plasmid

PVTBAV13661-2 2 ug
EUR 356.00

pLenti-RUNX3 shRNA-2 Plasmid

PVTBAV20583-2 2 ug
EUR 356.00

pLenti-Slc7a11 shRNA-2 Plasmid

PVTBAV21973-2 2 ug
EUR 356.00

pLenti-STAT3 shRNA-2 Plasmid

PVTBAV22921-2 2 ug
EUR 356.00

pLenti-XRCC5 shRNA-2 Plasmid

PVTBAV26238-2 2 ug
EUR 356.00

Mouse FGF-2 Recombinant Protein

R00121-2 5ug/vial
EUR 259.00
Description: FGF basic (FGF2) is a multipotential fibroblast growth factor that stimulates and supports proliferation, migration and differentiation. Mouse FGF basic (FGF-2) Recombinant Protein is purified FGF basic (FGF-2) produced in yeast.

Chicken IL-2 Recombinant Protein

R00387-2 5ug/vial
EUR 259.00
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Chicken IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Recombinant Human BD-2 Protein

PROTO15263-2 20ug
EUR 317.00
Description: Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The α-defensins are distinguished from the β-defensins by the pairing of their three disulfide bonds. To date, six human β-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. β-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The β-defensin proteins are expressed as the C-terminal portion of precursors and are released by proteolytic cleavage of a signal sequence and in some cases, a propeptide sequence. β-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds. Recombinant human BD-2 is a 4.3 kDa protein containing 41 amino acid residues.

Recombinant Human Relaxin-2 Protein

PROTP04090-2 25ug
EUR 317.00
Description: Relaxin-2 is a peptide hormone structurally related to insulin, which is expressed in the placenta, decidua, prostate, and in the ovary during pregnancy. Of the three known relaxin genes, Relaxin-2 is the only relaxin known to circulate in the blood. Relaxin-2 binds specifically to the LGR7 and LGR8 receptors, previously identified as an “orphan” G protein coupled receptors. Signaling by Relaxin-2 through its target receptors enhances the growth of pubic ligaments and ripening of the cervix during birth. Recombinant Relaxin-2 is a nonglycosylated 6.0 kDa disulfide linked heterodimeric protein consisting of a 24 amino acid A-chain and a 29 amino acid B-chain.

Recombinant Murine IL-2 Protein

PROTP04351-2 20ug
EUR 317.00
Description: IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes. Recombinant murine IL-2 is a 17.2 kDa protein, containing 149 amino acid residues.

Recombinant Human PAI-2 Protein

PROTP05120-2 10ug
EUR 317.00
Description: PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts. It exists predominantly as a 47 kDa nonglycosylated intracellular protein which can be induced to be secreted as 60 kDa glycoprotein. The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin. PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions. The physiological relevance of this property, which is neither a consequence of any mutation in the PAI-2 gene nor associated with any known disorder, is still unclear. However, it appears that the formation of intracellular dormant polymers may be important for the controlled release of the inhibitor from PAI-2 producing cells. Plasma levels of PAI-2 are usually low or undetectable, except during pregnancy and in some forms of monocytic leukemia. Secretion of PAI-2 from the placenta normally occurs during the third trimester of pregnancy and accounts for the dramatic increase in PAI-2 levels (up to 250 ng/ml), which are maintained at these levels until postpartum, and then rapidly decline. In addition to its vital role in protecting the placenta from degradation by uPA and/or uPA-activated proteases, PAI-2 has been shown to be essential for the prevention of metastatic spread of neck, lung and breast cancers. The beneficial effect of PAI-2 seen in these studies is presumed to stem from its ability to inhibit uPA-dependent cell dissemination. PAI-2 has also been reported to inhibit keratinocyte proliferation, and to participate in the innate immune response during viral infection. Recombinant human PAI-2 is a 415-residue nonglycosylated protein.

Recombinant Human MMP-2 Protein

PROTP08253-2 10ug
EUR 317.00
Description: Matrix metalloproteinases (MMPs) are a family of endoproteases that require zinc and calcium for expressing catalytic activity. These enzymes play a central role in the maintenance and remodeling of the extracellular matrix. Elevated expression of their activity, caused either by up-regulation of their expression or down-regulation of their cognate inhibitors, has been implicated in various degenerative disorders, including arthritis, cardiovascular disease, skeletal growth-plate disorders, and cancer metastasis. MMP-2 is a secreted collagenase with specificity toward Type IV, V, VII, and X collagens. Recombinant human MMP-2 is a 62.0 kDa protein containing the entire catalytic N-terminal domain and the C-terminal domain (552 amino acids).

Recombinant Human TFF-2 Protein

PROTQ03403-2 20ug
EUR 317.00
Description: The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464). Recombinant human TFF2 is a 12.0 kDa polypeptide of 107 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.

Anti-Adiponectin Receptor 2 (mouse) Antibody

A02218-2 200ug
EUR 498.00
Description: Goat Polyclonal Adiponectin Receptor 2 (mouse) Antibody. Validated in IF, IHC and tested in Mouse.

Anti-Anterior Gradient 2/AGR2 Antibody

A02922-2 100ug/vial
EUR 334.00

Anti-p56Dok-2 (Ab-299) Antibody

A07956-2 100ul
EUR 397.00
Description: Rabbit Polyclonal p56Dok-2 (Ab-299) Antibody. Validated in IF, IHC, WB and tested in Human.

Anti-COX2/Cyclooxygenase 2/PTGS2 Antibody

A00084-2 100ug/vial
EUR 294.00

Anti-beta 2 Microglobulin/B2m Antibody

A00456-2 100ug/vial
EUR 294.00

Anti-VEGF Receptor 2/KDR Antibody

A00901-2 100ug/vial
EUR 334.00

Anti-Bcl-2 Rabbit Monoclonal Antibody

M00040-2 100ug/vial
EUR 397.00
Description: Rabbit Monoclonal Bcl-2 Antibody. Validated in IF, WB and tested in Human, Mouse.

Anti-HIF-2-alpha/EPAS1 Antibody

PA1129-2 100ug/vial
EUR 294.00

ErbB2 ErbB-2 Human Recombinant Protein

PROTP04626-2 Regular: 20ug
EUR 317.00
Description: ErbB-2 Human Recombinant is a 43.4 kDa protein containing 397 amino acid residues of the human Herstatin, and an extra Methionine at N-Terminal (underlined), produced in E.coli.

Mouse Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82102 1 Kit Ask for price

Rat Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-82597 1 Kit Ask for price

Human Pancreas PrimaCell 2: Pancreatic Epithelial Cells

2-96123 1 Kit Ask for price

Anti-Beta 2 Microglobulin Antibody (monoclonal, 2H10)

M00456-2 100ug/vial
EUR 334.00

ENO2 Neurone Specific Enolase 2 Human protein

PROTP09104-2 Regular: 20ug
EUR 317.00
Description: Human Neurone Specific Enolase produced in Human CNS having a molecular mass of 45kDa.

IL-2

E13-013-2 50μg
EUR 505.00

FGF-2

E13-024-2 50μg
EUR 245.00

Custom Anti-Peptide antibodies 2 peptides (upto 20-aa, synthesis, 2 conjugation, 2 rabbits, 2 ELISA & 2 Aff. Purif.)

ABPEP-20A-2 1
EUR 3806.00

Anti-Rsk 2/MAPKAP Kinase 1b/RPS6KA3 Antibody

A02215-2 100ug/vial
EUR 334.00

Biotin-16-7-Deaza-7-Propargylamino-2'-dGTP

B8158-.2 200 µl (5 mM)
EUR 2436.00

Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348

M00084-2 100uL
EUR 397.00
Description: Anti-COX-2 Rabbit Monoclonal Antibody, Clone#RM348 tested in WB, IHC, reactive to Human

Recombinant Human TGF-Beta 2 (insect derived) Protein

PROTP61812-2 10ug
EUR 317.00
Description: The three mammalian isoforms of TGF-β, TGF-β1, β2, β3, signal through the same receptor and elicit similar biological responses. They are multifunctional cytokines that regulate cell proliferation, growth, differentiation and motility as well as synthesis and deposition of the extracellular matrix. They are involved in various physiological processes including embryogenesis, tissue remodeling and wound healing. They are secreted predominantly as latent complexes which are stored at the cell surface and in the extracellular matrix. The release of biologically active TGF-β isoform from a latent complex involves proteolytic processing of the complex and /or induction of conformational changes by proteins such as thrombospondin-1. TGF-β2 has been shown to exert suppressive effects on IL-2 dependent T-cell growth, and may also have an autocrine function in enhancing tumor growth by suppressing immuno-surveillance of tumor development. Recombinant human TGF-β2 is a 25.0 kDa protein composed of two identical 112 amino acid polypeptide chains linked by a single disulfide bond.
* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc.

Custom Anti-Peptide antibodies, 2 peptides (upto 20-aa; synthesis, 2 conjugation, 2 rabbits, 2 ELISA)

ABPEP-20-2 1
EUR 2356.00

AHSG Alpha-2-HS-Glycoprotein Human Recombinant Protein HEK

PROTP02765-2 Regular: 10ug
EUR 317.00
Description: AHSG Human Recombinant produced by transfected human cells is a single polypeptide chain containing 357 amino acids (19-367). AHSG is fused to an 8 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.

FGF-2 Fibroblast Growth Factor-Basic Human Recombinant Protein

PROTP09038-2 Regular: 50ug
EUR 317.00
Description: Fibroblast Growth Factor-2 Human Recombinant (FGF-2) produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 154 amino acids and having a molecular mass of 17.2kDa.;The FGF-b is purified by proprietary chromatographic techniques.

TIMP2 Tissue Inhibitor of Metalloprotease 2 Human Recombinant Protein

PROTP16035-2 Regular: 20ug
EUR 317.00
Description: TIMP2 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 194 amino acids and having a molecular mass of 21.8kDa. 

ExoStd? Lyophilized Exosome Standard (30 µg, Human Plasma, 2 vials)

M1040-2
EUR 593.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Plasma, 2 vials)

M1041-2
EUR 711.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Serum, 2 vials)

M1042-2
EUR 599.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Serum, 2 vials)

M1043-2
EUR 713.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Urine, 2 vials)

M1044-2
EUR 599.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Urine, 2 vials)

M1045-2
EUR 707.00

ExoStd? Lyophilized Exosome Standard (30 µg, Human Saliva, 2 vials)

M1046-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, Human Saliva, 2 vials)

M1047-2
EUR 729.00

ExoStd? Lyophilized Exosome Standard (30 µg, U87 MG, 2 vials)

M1054-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, U87 MG, 2 vials)

M1055-2
EUR 718.00

TNFR2 Tumor Necrosis Factor Receptor Type 2 Human Recombinant Protein

PROTP20333-2 Regular: 20ug
EUR 317.00
Description: TNFR2 Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 20kDa. The TNFR2 is purified by proprietary chromatographic techniques.

LCN2 Neutrophil Gelatinase Associated Lipocalin/Lipocalin-2 Human Recombinant Protein

PROTP80188-2 Regular: 10ug
EUR 317.00
Description: LCN2 Human Recombinant produced in E.Coli is a homodimeric non-glycosylated polypeptide chains consisting of two 178 amino acids and having a molecular mass of 41.0kDa. 

PLGF2 Human, Placenta Growth Factor-2 Human Recombinant Protein, CHO

PROTP49763-2 Regular: 25ug
EUR 317.00
Description: PLGF2 Human Recombinant (19-170 a.a.) produced in CHO is a disulfide-linked homodimeric, glycosylated, polypeptide chain containing 152 amino acids and having a molecular mass of 33kDa.;The PLGF-2 Human Recombinant protein is purified by proprietary chromatographic techniques.

B2M Human, Beta 2 Microglobulin Human Recombinant Protein, His Tag

PROTP61769-2 Regular: 5ug
EUR 317.00
Description: B2M Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 120 amino acids (1-119 a.a.) and having a molecular mass of 14 kDa. The B2M is fused to a 21 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

His-FGF-2

E13-027-2 50μg
EUR 245.00

IL-2-Fc

E13-m007-2 50μg
EUR 1090.00

ExoStd? Lyophilized Exosome Standard (30 µg, COLO1 cell line, 2 vials)

M1048-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, COLO1 cell line, 2 vials)

M1049-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, MM1 cell line, 2 vials)

M1050-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, MM1 cell line, 2 vials)

M1051-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, BLCL21 cell line, 2 vials)

M1052-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, BLCL21 cell line, 2 vials)

M1053-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, HCT116 cell line, 2 vials)

M1058-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, HCT116 cell line, 2 vials)

M1059-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, PC3 cell line, 2 vials)

M1060-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, PC3 cell line, 2 vials)

M1061-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, DAUD1 cell line, 2 vials)

M1064-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, DAUD1 cell line, 2 vials)

M1065-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, A549 cell line, 2 vials)

M1066-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, A549 cell line, 2 vials)

M1067-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, B16F10 cell line, 2 vials)

M1070-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, B16F10 cell line, 2 vials)

M1071-2
EUR 718.00

DCTN2 (1-403) Dynactin 2 (1-403 a.a.) Human Recombinant Protein

PROTQ13561-2 Regular: 20ug
EUR 317.00
Description: Dynactin 2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 426 amino acids (1-403 a.a) and having a molecular mass of 46.9kDa.;DCTN2 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

RARRES2 Human, Retinoic Acid Receptor Responder 2 Human Recombinant Protein,Sf9

PROTQ99969-2 Regular: 5ug
EUR 317.00
Description: RARRES2 produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 146 amino acids (21-157a.a.) and having a molecular mass of 16.9kDa. (Molecular size on SDS-PAGE will appear at approximately 18-28kDa). RARRES2 is expressed with a 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.

ExoStd? Lyophilized Exosome Standard (30 µg, BPH-1 cell line, 2 vials)

M1062-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, BPH-1 cell line, 2 vials)

M1063-2
EUR 718.00

ExoStd? Lyophilized Exosome Standard (30 µg, K-562 cell line, 2 vials)

M1068-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, K-562 cell line, 2 vials)

M1069-2
EUR 718.00

a.a.), TRAIL/APO 2 Ligand (114-281 a.a.) Human Recombinant Protein, Active

PROTP50591-2 Regular: 10ug
EUR 317.00
Description: Soluble TNF-related apoptosis-inducing ligand Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 169 amino acids _x000D_ (114-281) and having a molecular mass of 19.6 kDa._x000D_ The sTRAIL is purified by proprietary chromatographic techniques.

LH (Luteinizing Hormone) ELISA test

2 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of LH (Luteinizing Hormone)

ExoStd? Lyophilized Exosome Standard (30 µg, SK-N-SH cell line, 2 vials)

M1056-2
EUR 604.00

ExoStd? Lyophilized Exosome Standard (100 µg, SK-N-SH cell line, 2 vials)

M1057-2
EUR 718.00

VEGFR2-Fc Vascular Endothelial Growth Factor Receptor-2 Fc Chimera Human Recombinant Protein

PROTP35968-2 Regular: 10ug
EUR 317.00
Description: Soluble VEGFR2 Fc Human Recombinant fused with the Fc part of human IgG1 produced in baculovirus is a disulfide-linked homodimeric, glycosylated, polypeptide containing 968 amino acids and having a molecular mass of 145 kDa. The soluble receptor protein contains only the first 7 extracellular domains, which contain all the information necessary for ligand binding.

SOX2 Human, SRY (sex determining region Y)-box 2 Human Recombinant Protein, TAT

PROTP48431-2 Regular: 25ug
EUR 317.00
Description: Sox2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 330 amino acids (317 aa residues of the full length Sox2) and having a molecular mass of 36kDa.;Sox2 is fused to a 13 amino acid TAT peptide at C-terminus (GGYGRKKRRQRRR) & purified by proprietary chromatographic techniques.

Custom production of antibodies in 2 Chickens using supplied antigen (std 63 days protocol)

CHI-2 1
EUR 1138.00

Custom production of antibodies in 2 Rabbits using supplied antigen (std 63 days protocol)

RAB-2 1
EUR 1138.00

Custom production of antibodies in 2 G. Pigs using supplied antigen (std 63 days protocol)

GPI-2 1
EUR 1138.00

Trichosanthes japonica agglutinin 2 (TJA)

05-0033-2 2 mg
EUR 305.00

Multiple Tumor Tissue Array - 47 different tumors and their corresponding normal tissues, plus 2 control spots

T8235713-2 2 slides
EUR 391.00
Description: Our tissue products are produced by strictly following the IRB ethical standards and procedures and from highest quality tissues. Immediately after collection the tissues are placed in liquid nitrogen and examined by certified pathologists. The thickness of each individual section is ~5um. They are Hematoxylin and Eosin stained and quality tested by immunostaining with anti-beta-actin antibodies. Our tissue products are suitable for various studies on cellular level (RNA localization, Protein expression, etc.) on both normal and pathological cases. It is also an excellent control and educational tool.

Lethal factor Protease Substrate 2, pNA derivative MEk2 peptide substrate for high-throughput screening of LF inhibitors (14aa)

LFPS-2 1 mg
EUR 408.00

Human pre-microRNA Expression Construct 146a-2

PMIRH146a-PA-2 Bacterial Streak
EUR 684.00
  • Category: MicroRNA Tools

miRZip-92-2* anti-miR-92-2* microRNA star construct

MZIP92-2*-PA-1 Bacterial Streak
EUR 684.00
  • Category: MicroRNA Tools

Rabbit Anti HIV-1 gp120 protein IgG, clone 2

AB-21010-2 100 ul
EUR 469.00

Mouse Monoclonal anti-PEG (backbone specific) IgG (Clone #2)

PEG13-M-2 100 ug
EUR 482.00

Mouse Monoclonal anti-Clostridium difficile toxin A IgG (Clone #2)

CDTA12-M-2 100 ug
EUR 482.00

Mouse Monoclonal anti-Clostridium difficile toxin B IgG (Clone #2)

CDTB12-M-2 100 ug
EUR 482.00

AXYGEN® AXYPET® PRO 0.1 - 2 ΜL SINGLE-CHANNEL PIPETTOR, AUTOCLAVABLE

AP-2-P 1/pk
EUR 202.00
Description: Corning and Axygen Liquid Handling Equipment; Axypet Pipettors and Motopet Pipet Controller

Monoclonal Anti-Dengue Virus Type 1-4 (pan, NS1) IgG, clone 2 (pairs with clone 1)

AB-21122-2 0.5 ml
EUR 529.00

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

DL-LAB7-2-Hu-192 1 kit of 192 tests
EUR 913.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2)

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

DL-LAB7-2-Hu-48 1 kit of 48 tests
EUR 398.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2)

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

DL-LAB7-2-Hu-96 1 kit of 96 tests
EUR 526.00
Description: An ELISA kit based on the sandwich method for detection and quantification of Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2)

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

DLR-LAB7-2-Hu-48T 48T
EUR 425.00
  • Should the Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

DLR-LAB7-2-Hu-96T 96T
EUR 548.00
  • Should the Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) in samples from tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

RD-LAB7-2-Hu-48Tests 48 Tests
EUR 418.00

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

RD-LAB7-2-Hu-96Tests 96 Tests
EUR 575.00

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

RDR-LAB7-2-Hu-48Tests 48 Tests
EUR 436.00

Human B-Lymphocyte Activation Antigen B7-2 (LAB7-2) ELISA Kit

RDR-LAB7-2-Hu-96Tests 96 Tests
EUR 601.00

SH2 Domain Ligand (2) (AA: Glu-Pro-Gln-pTyr-Glu-Glu-Ile-Pro-Ile-Tyr-Leu) (MW: 1473.57)

SP-101402-2 2mg
EUR 164.00

Caspase 2 Substrate 1m (ICH-1), fluorogenic; Ac-VDVAD-AMC (AA: Ac-Val-Asp-Val-Ala-Asp-AMC) (MW: 716.8)

SP-101342-2 2mg
EUR 202.00

BCIP, Na (5-bromo-4-chloro-3-indoxyl phosphate, disodium salt): (5g)

10001-2 5G
EUR 1282.00
Description: Minimum order quantity: 1 unit of 5G

BCIP, toluidine (5-bromo-4-chloro-3-indoxyl phosphate, p-toluidine salt): (5g)

10002-2 5G
EUR 1241.00
Description: Minimum order quantity: 1 unit of 5G

NBT (nitro blue tetrazolium, chloride)

10008-2 5G
EUR 553.00
Description: Minimum order quantity: 1 unit of 5G

X-Gal (5-bromo-4-chloro-3-indolyl-beta-galactopyranoside): (5g)

10011-2 5G
EUR 500.00
Description: Minimum order quantity: 1 unit of 5G

IPTG

10021-2 5G
EUR 210.00
Description: Minimum order quantity: 1 unit of 5G

D-Luciferin, free acid

10100-2 1G
EUR 714.00
Description: Minimum order quantity: 1 unit of 1G

D-Luciferin, potassium salt

10101-2 1G
EUR 714.00
Description: Minimum order quantity: 1 unit of 1G

D-Luciferin, sodium salt

10102-2 1G
EUR 714.00
Description: Minimum order quantity: 1 unit of 1G

Coelenterazine (native)

10110-2 250uG
EUR 186.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine h

10111-2 250uG
EUR 186.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine cp

10112-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine hcp

10113-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine f

10114-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine n

10115-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine ip

10116-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine fcp

10117-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Goat Anti-Human IgG (Fc) IgG, unlabeled

10119-2 1 mg
EUR 225.00

Coelenterazine i

10121-2 250uG
EUR 259.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine e

10124-2 250uG
EUR 399.00
Description: Minimum order quantity: 1 unit of 250uG

Coelenterazine 400A (DeepBlueC, a trademark of PE)

10125-2 250uG
EUR 191.00
Description: Minimum order quantity: 1 unit of 250uG

LUMITEIN PROTEIN GEL STAIN, 1X

21001-2 5L
EUR 802.00
Description: Minimum order quantity: 1 unit of 5L

LUMITEIN PROTEIN GEL STAIN, 100X

21002-2 50ML
EUR 634.00
Description: Minimum order quantity: 1 unit of 50ML

Smo Antagonist, SA1

2154-2
EUR 137.00

Smo Antagonist, SA9

2155-2
EUR 137.00

Smo Antagonist, SA10

2159-2
EUR 137.00

Goat Gamma Globulin

22005-2 10g
EUR 553.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Goat gamma globulin is purified from serum obtained from normal healthy animals (male and female) by using various fractionation procedures followed by dialysis against low ionic strength buffer. It is in lyophilized powder form with purity of 98% or more. Protein by weight: O.D. 280 nm E1%1.39: ? 85% - Residual salts, lipids, etc. comprise the rest of the weight.

Bovine Gamma Globulin

27005-2 100g
EUR 454.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Bovine gamma globulin is purified from serum obtained from normal healthy animals from USA (male and female) by using various fractionation procedures followed by dialysis against low ionic strength buffer. It is in lyophilized powder form with purity of 98% or more. Protein by weight: O.D. 280 nm E1%1.39: ? 85% - Residual salts, lipids, etc. comprise the rest of the weight.

EZH2 Inhibitor, EPZ005687

2364-2
EUR 175.00

EZSolution? EPZ005687

2375-2
EUR 185.00

Rabbit Gamma Globulin

21005-2 10g
EUR 429.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Rabbit gamma globulin is purified from serum obtained from normal healthy rabbits (male and female) by using various fractionation procedures. It is in lyophilized powder form with purity of 95% or more. Protein by weight: O.D. 280 nm E1%1.39: ? 85% - Residual salts, lipids, etc. comprise the rest of the weight.

Acetic Acid (50 mM)

2112-2
EUR 55.00

Mitomycin C

2713-2
EUR 120.00

AAL-993

2740-2
EUR 142.00

SirtACt

2741-2
EUR 153.00

Horse Serum Sterile, Non-Hemolyzed

39321-2 3L
EUR 429.00
  • All products from Pel-Freez are available in Europe and worldwide via Gentaur. If you cannot find the item you need send us an inquiry and we will be in touch with you with pricing and delivery information in less than 12 hours.
Description: Whole blood is collected from both male and female healthy horses living in a herd and are 1+ years of age. The blood is refrigerated within 6 hours after collection and is processed within 24 hours and frozen at -20°C. Filtered through a 0.22 micron filter.

TARGATT? attp Mouse B6 (Age: 29-35 days) *Ship from CRL

549-2 1 female Ask for price
Description: N/A

SCH-1473759

A3804-2 2 mg
EUR 267.00
Description: IC50 Value: 4 nM (IC50) for Aurora A, and below or equal to 13 nM (IC50) for Aurora B [1]. SCH 1473759, a novel sub-nanomolar Aurora A/B inhibitor.

Silvestrol

A3818-2 2 mg
EUR 2312.00
Description: Silvestrol inhibited protein synthesis in MDA-MB-231 breast and PC-3 prostate cancer cell lines with IC50 ~60 nM following a 1 h exposure) [1]. Silvestrol inhibited cell growth with an IC50 of 12.5-86 nM in four different HCC cell lines [3].

Taranabant

A3858-2 2 mg
EUR 212.00
Description: Taranabant is a Novel, Acyclic Cannabinoid-1 Receptor Inverse Agonist ?CB1 Antagonist?for the Treatment of Obesity.

BMS-708163 (Avagacestat)

A4022-2 2 mg
EUR 137.00
Description: BMS-708163 is a potent selective and orally bioavailable inhibitor of ?-secretase with IC50 value of 0.3nM [1].The cleavage of amyloid precusor protein APP by ?-secretase causes the production of A?40 and A?42, which are cytotoxic and cause AD.

Danoprevir (RG7227)

A4024-2 2 mg
EUR 148.00
Description: Danoprevir (R7227) is a potent and selective inhibitor of Hepatitis C Virus (HCV) NS3/4A protease, a chymotrypsin-like serine protease playing an essential role in the viral replication process of HCV, that non-covalently binds to and hence inhibits HCV NS3 protease.

Telaprevir (VX-950)

A4031-2 2 mg
EUR 142.00
Description: Telaprevir (also known as VX-950), derived from the viral NS5A/5B substrate of the protease through structure-based techniques, is a novel and potent inhibitor of hepatitis C virus (HCV) NS3-4A protease, which covalently and reversibly inhibit the NS3-4A protease.

AR-42 (OSU-HDAC42)

A4104-2 2 mg
EUR 108.00
Description: AR-42 (also known as OSU-HDAC42), a derivative of hydroxamate-tethered phenylbutyrate, is a novel and potent inhibitor of histone deacetylase (HDAC) that potently inhibits the activity of HDAC with 50% inhibition concentration IC50 value of 16 nM.

JNJ-7706621

A4115-2 2 mg
EUR 148.00
Description: JNJ-7706621 is a dual inhibitor of cyclin-dependent kinases (CDK) and Aurora kinases that potently inhibits CDK1, CDK2, CDK3, CDK4, CDK6, Aurora-A, and Aurora-B in vitro.

AT9283

A4117-2 2 mg
EUR 131.00
Description: AT9283, a synthetic small heterocyclic molecule discovered using a fragment-based approach, is a novel inhibitor of aurora kinase, a family of serine/threonine kinases regulating both mitosis and meiosis, that potently inhibits Aurora kinases A and B.

Amuvatinib (MP-470, HPK 56)

A4237-2 2 mg
EUR 148.00
Description: Amuvatinib (also known as MP-470 or HPK 56), a synthetic carbothioamide, is a novel and potent tyrosine kinase inhibitor, which exerts in vitro and in vivo activities against multiple targets including mutant KIT, platelet-derived growth factor receptor alpha (PDGFR?) and DNA repair.

NVP-AEW541

A2278-2 2 mg
EUR 154.00
Description: NVP-AEW541 is a novel, potent and selective inhibitor of IGF-IR kinase with IC50 value of 0.086 ?M [1]. NVP-AEW541 is a pyrrolo(2,3-d) pyrimidine derivative.

BMX-IN-1

A3260-2 2 mg
EUR 160.00
Description: BMX-IN-1 is a highly selective and irreversible inhibitor of BMX kinase [1].BMX, also known as ETK, is a member of Tec family and plays an important role in regulating ischemia-mediated arteriogenesis and lymphangiogenesis

Cinaciguat

A3314-2 2 mg
EUR 231.00
Description: Cinaciguat, also known as BAY-58-2667, is a NO-independent activator for sGC with EC50 of ?10 nM for heme-free/oxidized sGC.

Istaroxime hydrochloride

A3508-2 2 mg
EUR 232.00
Description: Istaroxime hydrochloride(PST2744) is a novel inhibitor of Na+/K+-ATPase with IC50 value of 0.43±0.15?M [1].

MB05032

A3586-2 2 mg
EUR 228.00
Description: MB05032 is a potent and selective GNG inhibitor targeted the AMP binding site of fructose 1,6-bisphosphatase (FBPase) with an IC50 value of 16 nM [1].Gluconeogenesis (GNG) is a metabolic pathway which could result in the generation of glucose from certain non-carbohydratecarbon substrates.

Anti-XPA Antibody

A01182-2 100ug/vial
EUR 294.00

Anti-BNP/NPPB Antibody

A01186-2 100ug/vial
EUR 294.00

Anti-Choline Acetyltransferase/CHAT Antibody

A01192-2 100ug/vial
EUR 294.00

Anti-VCAM1 Antibody

A01199-2 100ug/vial
EUR 334.00

Anti-HDAC-5 (internal) Antibody

A01230-2 100ug
EUR 455.00
Description: Rabbit Polyclonal HDAC-5 (internal) Antibody. Validated in IP and tested in Human.

Anti-Lamin B Receptor/LBR Antibody

A01238-2 100ug/vial
EUR 334.00

Anti-HAUSP/USP7 Antibody

A01239-2 100ug/vial
EUR 334.00

Anti-LPP Antibody

A01240-2 100ug/vial
EUR 334.00

Anti-Human Serum Albumin Antibody Fluorescein Conjugated

A01245-2 1mg
EUR 1232.00
Description: Rabbit Polyclonal Human Serum Albumin Antibody Fluorescein Conjugated. Validated in WB and tested in Human.

Anti-MDC1 Antibody

A01252-2 100ug/vial
EUR 334.00

Subsequent analysis of morphology and immunophenotyping was consistent with primary diffuse large B-cell lymphoma of the central nervous system. Use of Humira was discontinued. Following combination therapy with high dose methotrexate and rituximab along with twenty sessions of cranial radiation therapy, the patient is disease free at fourteen months follow up since surgery.This illustrates the first case of a possible association of central nervous lymphoma and adalimumab.